SUDS3
| Suppressor of defective silencing 3 homolog (S. cerevisiae) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SUDS3 ; SAP45; SDS3 | ||||||||||||
| External IDs | OMIM: 608250 MGI: 1919204 HomoloGene: 15906 GeneCards: SUDS3 Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 64426 | 71954 | |||||||||||
| Ensembl | ENSG00000111707 | ENSMUSG00000066900 | |||||||||||
| UniProt | Q9H7L9 | Q8BR65 | |||||||||||
| RefSeq (mRNA) | NM_022491 | NM_001122666 | |||||||||||
| RefSeq (protein) | NP_071936 | NP_001116138 | |||||||||||
| Location (UCSC) | Chr 12: 118.81 – 118.86 Mb | Chr 5: 117.09 – 117.12 Mb | |||||||||||
| PubMed search | |||||||||||||
Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene.[1][2]
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM][2]
Interactions
SUDS3 has been shown to interact with HDAC1,[1][3] Host cell factor C1,[4] SIN3B[1] and SIN3A.[1][3]
References
- ↑ 1.0 1.1 1.2 1.3 Alland L, David G, Shen-Li H, Potes J, Muhle R, Lee HC, Hou H Jr, Chen K, DePinho RA (Mar 2002). "Identification of Mammalian Sds3 as an Integral Component of the Sin3/Histone Deacetylase Corepressor Complex". Mol Cell Biol 22 (8): 2743–50. doi:10.1128/MCB.22.8.2743-2750.2002. PMC 133736. PMID 11909966.
- ↑ 2.0 2.1 "Entrez Gene: SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)".
- ↑ 3.0 3.1 Fleischer, Tracey C; Yun Ui Jeong; Ayer Donald E (May 2003). "Identification and Characterization of Three New Components of the mSin3A Corepressor Complex". Mol. Cell. Biol. (United States) 23 (10): 3456–67. doi:10.1128/MCB.23.10.3456-3467.2003. ISSN 0270-7306. PMC 164750. PMID 12724404.
- ↑ Wysocka, Joanna; Myers Michael P; Laherty Carol D; Eisenman Robert N; Herr Winship (Apr 2003). "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1". Genes Dev. (United States) 17 (7): 896–911. doi:10.1101/gad.252103. ISSN 0890-9369. PMC 196026. PMID 12670868.
Further reading
- Olsen JV; Blagoev B; Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Fleischer TC, Yun UJ, Ayer DE (2003). "Identification and Characterization of Three New Components of the mSin3A Corepressor Complex". Mol. Cell. Biol. 23 (10): 3456–67. doi:10.1128/MCB.23.10.3456-3467.2003. PMC 164750. PMID 12724404.
- Wysocka J; Myers MP; Laherty CD et al. (2003). "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1". Genes Dev. 17 (7): 896–911. doi:10.1101/gad.252103. PMC 196026. PMID 12670868.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hattori A; Okumura K; Nagase T et al. (2001). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi:10.1093/dnares/7.6.357. PMID 11214971.