STRN
| Striatin, calmodulin binding protein | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | STRN ; SG2NA | ||||||||||||
| External IDs | OMIM: 614765 MGI: 1333757 HomoloGene: 2380 GeneCards: STRN Gene | ||||||||||||
| |||||||||||||
| RNA expression pattern | |||||||||||||
 | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 6801 | 268980 | |||||||||||
| Ensembl | ENSG00000115808 | ENSMUSG00000024077 | |||||||||||
| UniProt | O43815 | O55106 | |||||||||||
| RefSeq (mRNA) | NM_003162 | NM_011500 | |||||||||||
| RefSeq (protein) | NP_003153 | NP_035630 | |||||||||||
| Location (UCSC) | Chr 2: 37.07 – 37.19 Mb | Chr 17: 78.65 – 78.74 Mb | |||||||||||
| PubMed search | |||||||||||||
Striatin is a protein that in humans is encoded by the STRN gene.[1][2][3]
Interactions
STRN has been shown to interact with STK25,[4] PDCD10,[4] CTTNBP2,[4] TRAF3IP3,[4] STRN3,[4] MOBKL3,[4] STK24,[4][5] PPP2CA,[4] RP6-213H19.1,[4] PPP2R1A,[4] CTTNBP2NL[4] and FAM40A.[4]
References
- ↑ Moqrich A, Mattei MG, Bartoli M, Rakitina T, Baillat G, Monneron A, Castets F (Sep 1998). "Cloning of human striatin cDNA (STRN), gene mapping to 2p22-p21, and preferential expression in brain". Genomics 51 (1): 136–9. doi:10.1006/geno.1998.5342. PMID 9693043.
- ↑ Castets F, Bartoli M, Barnier JV, Baillat G, Salin P, Moqrich A, Bourgeois JP, Denizot F, Rougon G, Calothy G, Monneron A (Oct 1996). "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons". J Cell Biol 134 (4): 1051–62. doi:10.1083/jcb.134.4.1051. PMC 2120968. PMID 8769426.
- ↑ "Entrez Gene: STRN striatin, calmodulin binding protein".
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 4.10 4.11 Goudreault, Marilyn; D'Ambrosio Lisa M, Kean Michelle J, Mullin Michael J, Larsen Brett G, Sanchez Amy, Chaudhry Sidharth, Chen Ginny I, Sicheri Frank, Nesvizhskii Alexey I, Aebersold Ruedi, Raught Brian, Gingras Anne-Claude (Jan 2009). "A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein". Mol. Cell Proteomics (United States) 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.
- ↑ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Further reading
- Moreno CS, Park S, Nelson K et al. (2000). "WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A". J. Biol. Chem. 275 (8): 5257–63. doi:10.1074/jbc.275.8.5257. PMC 3505218. PMID 10681496.
- Gaillard S, Bartoli M, Castets F, Monneron A (2001). "Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1". FEBS Lett. 508 (1): 49–52. doi:10.1016/S0014-5793(01)03020-4. PMID 11707266.
- Huang Y, Tang R, Dai J et al. (2002). "A novel human hydroxysteroid dehydrogenase like 1 gene (HSDL1) is highly expressed in reproductive tissues". Mol. Biol. Rep. 28 (4): 185–91. doi:10.1023/A:1015726217890. PMID 12153137.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Colland F, Jacq X, Trouplin V et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Lu Q, Pallas DC, Surks HK et al. (2005). "Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor α". Proc. Natl. Acad. Sci. U.S.A. 101 (49): 17126–31. doi:10.1073/pnas.0407492101. PMC 534607. PMID 15569929.
- Hillier LW, Graves TA, Fulton RS et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
- Ewing RM, Chu P, Elisma F et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.