SMC4

Structural maintenance of chromosomes 4
Identifiers
SymbolsSMC4 ; CAP-C; CAPC; SMC-4; SMC4L1; hCAP-C
External IDsOMIM: 605575 MGI: 1917349 HomoloGene: 4015 GeneCards: SMC4 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez1005170099
EnsemblENSG00000113810ENSMUSG00000034349
UniProtQ9NTJ3Q8CG47
RefSeq (mRNA)NM_001002799NM_133786
RefSeq (protein)NP_001002800NP_598547
Location (UCSC)Chr 3:
160.12 – 160.15 Mb
Chr 3:
69 – 69.03 Mb
PubMed search

Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded by the SMC4 gene.[1][2][3] SMC-4 is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation.

References

  1. Schmiesing JA, Ball AR Jr, Gregson HC, Alderton JM, Zhou S, Yokomori K (Nov 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics". Proc Natl Acad Sci U S A 95 (22): 12906–11. doi:10.1073/pnas.95.22.12906. PMC 23650. PMID 9789013.
  2. Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y (Jun 1999). "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family". J Hum Genet 44 (3): 197–202. doi:10.1007/s100380050142. PMID 10319587.
  3. "Entrez Gene: SMC4 structural maintenance of chromosomes 4".

Further reading

External links