SLC9A10

Solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Identifiers
SymbolsSLC9C1 ; NHE; SLC9A10; sperm-NHE
External IDsOMIM: 612738 MGI: 2685456 HomoloGene: 19505 IUPHAR: 957 GeneCards: SLC9C1 Gene
Orthologs
SpeciesHumanMouse
Entrez285335208169
EnsemblENSG00000172139ENSMUSG00000033210
UniProtQ4G0N8Q6UJY2
RefSeq (mRNA)NM_183061NM_198106
RefSeq (protein)NP_898884NP_932774
Location (UCSC)Chr 3:
111.86 – 112.01 Mb
Chr 16:
45.54 – 45.61 Mb
PubMed search

Sodium/hydrogen exchanger 10, also known as solute carrier family 9 member 10, is a protein that in humans is encoded by the SLC9A10 gene.[1][2]

Function

SLC9A10 is a member of the sodium-hydrogen exchanger (NHE) family and is required for male fertility and sperm motility.[1][3]

References

  1. 1.0 1.1 "Entrez Gene: solute carrier family 9".
  2. Oduru S, Campbell JL, Karri S, Hendry WJ, Khan SA, Williams SC (June 2003). "Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs". BMC Genomics 4 (1): 22. doi:10.1186/1471-2164-4-22. PMC 161800. PMID 12783626.
  3. Wang D, King SM, Quill TA, Doolittle LK, Garbers DL (December 2003). "A new sperm-specific Na+/H+ exchanger required for sperm motility and fertility". Nat. Cell Biol. 5 (12): 1117–22. doi:10.1038/ncb1072. PMID 14634667.