SLC2A10

Solute carrier family 2 (facilitated glucose transporter), member 10
Identifiers
SymbolsSLC2A10 ; ATS; GLUT10
External IDsOMIM: 606145 MGI: 2156687 HomoloGene: 38551 IUPHAR: 886 GeneCards: SLC2A10 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez81031170441
EnsemblENSG00000197496ENSMUSG00000027661
UniProtO95528Q8VHD6
RefSeq (mRNA)NM_030777NM_130451
RefSeq (protein)NP_110404NP_569718
Location (UCSC)Chr 20:
45.34 – 45.36 Mb		Chr 2:
165.5 – 165.52 Mb
PubMed search

Solute carrier family 2, facilitated glucose transporter member 10 is a protein that in humans is encoded by the SLC2A10 gene.[1][2]

SLC2A10 is a member of the facilitative glucose transporter family, which plays a significant role in maintaining glucose homeostasis.[supplied by OMIM][2]

See also

References

  1. ↑ McVie-Wylie AJ, Lamson DR, Chen YT (Mar 2001). "Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility". Genomics 72 (1): 113–7. doi:10.1006/geno.2000.6457. PMID 11247674.
  2. ↑ 2.0 2.1 "Entrez Gene: SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10".

Further reading

  • Dawson PA, Mychaleckyj JC, Fossey SC et al. (2001). "Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1". Mol. Genet. Metab. 74 (1–2): 186–99. doi:10.1006/mgme.2001.3212. PMID 11592815.
  • Deloukas P, Matthews LH, Ashurst J et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
  • Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Richardson S, Neama G, Phillips T et al. (2003). "Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation". Osteoarthr. Cartil. 11 (2): 92–101. doi:10.1053/joca.2002.0858. PMID 12554125.
  • Wood IS, Hunter L, Trayhurn P (2003). "Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues". Biochem. Biophys. Res. Commun. 308 (1): 43–9. doi:10.1016/S0006-291X(03)01322-6. PMID 12890477.
  • Andersen G, Rose CS, Hamid YH et al. (2003). "Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits". Diabetes 52 (9): 2445–8. doi:10.2337/diabetes.52.9.2445. PMID 12941788.
  • Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Zaidi SH, Peltekova V, Meyer S et al. (2005). "A family exhibiting arterial tortuosity syndrome displays homozygosity for markers in the arterial tortuosity locus at chromosome 20q13". Clin. Genet. 67 (2): 183–8. doi:10.1111/j.1399-0004.2004.00391.x. PMID 15679832.
  • Mohlke KL, Skol AD, Scott LJ et al. (2005). "Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns". Mol. Genet. Metab. 85 (4): 323–7. doi:10.1016/j.ymgme.2005.04.011. PMID 15936967.
  • Segade F, Allred DC, Bowden DW (2005). "Functional characterization of the promoter of the human glucose transporter 10 gene". Biochim. Biophys. Acta 1730 (2): 147–58. doi:10.1016/j.bbaexp.2005.06.012. PMID 16051383.
  • Coucke PJ, Willaert A, Wessels MW et al. (2006). "Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome". Nat. Genet. 38 (4): 452–7. doi:10.1038/ng1764. PMID 16550171.
  • Lin WH, Chuang LM, Chen CH et al. (2006). "Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population". Diabetologia 49 (6): 1214–21. doi:10.1007/s00125-006-0218-3. PMID 16586067.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.