SLC27A1
Long-chain fatty acid transport protein 1 is a protein that in humans is encoded by the SLC27A1 gene.[1][2]
Structure
The SLC27A1 gene is located on the 19th chromosome, with its specific location being 19p13.11. The gene contains 15 exons. [2] SLC27A1 encodes a 71.1 kDa protein that is composed of 646 amino acids; 26 peptides have been observed through mass spectrometry data.[3][4]
See also
- SLC27A1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Solute carrier family
References
- ↑ Martin G, Nemoto M, Gelman L, Geffroy S, Najib J, Fruchart JC, Roevens P, de Martinville B, Deeb S, Auwerx J (Sep 2000). "The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression". Genomics 66 (3): 296–304. doi:10.1006/geno.2000.6191. PMID 10873384.
- ↑ 2.0 2.1 "Entrez Gene: SLC27A1 solute carrier family 27 (fatty acid transporter), member 1".
- ↑ ]Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS et al. (Oct 2013). "Integration of cardiac proteome biology and medicine by a specialized knowledgebase". Circulation Research 113 (9): 1043–53. doi:10.1161/CIRCRESAHA.113.301151. PMC 4076475. PMID 23965338.
- ↑ "Long-chain fatty acid transport protein 1". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB).
Further reading
- Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J (2006). "Lack of association between certain candidate gene polymorphisms and the metabolic syndrome.". Mol. Genet. Metab. 86 (1–2): 293–9. doi:10.1016/j.ymgme.2005.05.006. PMID 15978856.
- García-Martínez C; Marotta M; Moore-Carrasco R et al. (2005). "Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells". Am. J. Physiol., Cell Physiol. 288 (6): C1264–72. doi:10.1152/ajpcell.00271.2004. PMID 15897321.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gertow K; Skoglund-Andersson C; Eriksson P et al. (2003). "A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution". Atherosclerosis 167 (2): 265–73. doi:10.1016/S0021-9150(02)00454-9. PMID 12818409.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hatch GM; Smith AJ; Xu FY et al. (2003). "FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells". J. Lipid Res. 43 (9): 1380–9. doi:10.1194/jlr.M200130-JLR200. PMID 12235169.
- Hirsch D, Stahl A, Lodish HF (1998). "A family of fatty acid transporters conserved from mycobacterium to man". Proc. Natl. Acad. Sci. U.S.A. 95 (15): 8625–9. doi:10.1073/pnas.95.15.8625. PMC 21126. PMID 9671728.
- Schaffer JE, Lodish HF (1994). "Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein". Cell 79 (3): 427–36. doi:10.1016/0092-8674(94)90252-6. PMID 7954810.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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