SH3PXD2A
| SH3 and PX domains 2A | |||||||||||||
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 Rendering based on PDB 2DNU. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | SH3PXD2A ; FISH; SH3MD1; TKS5 | ||||||||||||
| External IDs | MGI: 1298393 HomoloGene: 7317 GeneCards: SH3PXD2A Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 9644 | 14218 | |||||||||||
| Ensembl | ENSG00000107957 | ENSMUSG00000053617 | |||||||||||
| UniProt | Q5TCZ1 | O89032 | |||||||||||
| RefSeq (mRNA) | NM_014631 | NM_001164717 | |||||||||||
| RefSeq (protein) | NP_055446 | NP_001158189 | |||||||||||
| Location (UCSC) | Chr 10: 105.35 – 105.62 Mb | Chr 19: 47.26 – 47.46 Mb | |||||||||||
| PubMed search | |||||||||||||
SH3 and PX domain-containing protein 2A is a protein that in humans is encoded by the SH3PXD2A gene.[1][2]
References
- ↑ Lock P, Abram CL, Gibson T, Courtneidge SA (Sep 1998). "A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate". EMBO J 17 (15): 4346–57. doi:10.1093/emboj/17.15.4346. PMC 1170768. PMID 9687503.
- ↑ "Entrez Gene: SH3PXD2A SH3 and PX domains 2A".
Further reading
- Ishikawa K, Nagase T, Nakajima D et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
- Abram CL, Seals DF, Pass I et al. (2003). "The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.". J. Biol. Chem. 278 (19): 16844–51. doi:10.1074/jbc.M300267200. PMID 12615925.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brandenberger R, Wei H, Zhang S et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Deloukas P, Earthrowl ME, Grafham DV et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
- Seals DF, Azucena EF, Pass I et al. (2005). "The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells.". Cancer Cell 7 (2): 155–65. doi:10.1016/j.ccr.2005.01.006. PMID 15710328.
- Malinin NL, Wright S, Seubert P et al. (2005). "Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity.". Proc. Natl. Acad. Sci. U.S.A. 102 (8): 3058–63. doi:10.1073/pnas.0408237102. PMC 549444. PMID 15710903.
- Harold D, Jehu L, Turic D et al. (2007). "Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.". Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (4): 448–52. doi:10.1002/ajmg.b.30456. PMID 17440933.