SH3BP5
| SH3-domain binding protein 5 (BTK-associated) | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | SH3BP5 ; SAB; SH3BP-5 | ||||||||||||
| External IDs | OMIM: 605612 MGI: 1344391 HomoloGene: 23450 GeneCards: SH3BP5 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 9467 | 24056 | |||||||||||
| Ensembl | ENSG00000131370 | ENSMUSG00000021892 | |||||||||||
| UniProt | O60239 | Q9Z131 | |||||||||||
| RefSeq (mRNA) | NM_001018009 | NM_011894 | |||||||||||
| RefSeq (protein) | NP_001018009 | NP_036024 | |||||||||||
| Location (UCSC) | Chr 3: 15.3 – 15.38 Mb | Chr 14: 31.36 – 31.44 Mb | |||||||||||
| PubMed search | |||||||||||||
SH3 domain-binding protein 5 is a protein that in humans is encoded by the SH3BP5 gene.[1][2][3]
Interactions
SH3BP5 has been shown to interact with Bruton's tyrosine kinase[1][2] and MAPK8.[4]
References
- ↑ 1.0 1.1 Matsushita M, Yamadori T, Kato S, Takemoto Y, Inazawa J, Baba Y, Hashimoto S, Sekine S, Arai S, Kunikata T, Kurimoto M, Kishimoto T, Tsukada S (June 1998). "Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK)". Biochem Biophys Res Commun 245 (2): 337–43. doi:10.1006/bbrc.1998.8420. PMID 9571151.
- ↑ 2.0 2.1 Yamadori T, Baba Y, Matsushita M, Hashimoto S, Kurosaki M, Kurosaki T, Kishimoto T, Tsukada S (June 1999). "Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein". Proc Natl Acad Sci U S A 96 (11): 6341–6. doi:10.1073/pnas.96.11.6341. PMC 26883. PMID 10339589.
- ↑ "Entrez Gene: SH3BP5 SH3-domain binding protein 5 (BTK-associated)".
- ↑ Wiltshire, Carolyn; Matsushita Masato; Tsukada Satoshi; Gillespie David A F; May Gerhard H W (November 2002). "A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria". Biochem. J. (England) 367 (Pt 3): 577–85. doi:10.1042/BJ20020553. ISSN 0264-6021. PMC 1222945. PMID 12167088.
Further reading
- Baba Y, Matsushita M, Matsuda Y et al. (2000). "Assignment of SH3BP5/Sh3bp5 encoding sab, an SH3 domain-binding protein which preferentially associates with Bruton's tyrosine kinase, to human chromosome 1q43 and mouse chromosome 14B by in situ hybridization.". Cytogenet. Cell Genet. 87 (3-4): 221–2. doi:10.1159/000015430. PMID 10702676.
- Wiltshire C, Matsushita M, Tsukada S et al. (2002). "A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria.". Biochem. J. 367 (Pt 3): 577–85. doi:10.1042/BJ20020553. PMC 1222945. PMID 12167088.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brandenberger R, Wei H, Zhang S et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Court NW, Kuo I, Quigley O, Bogoyevitch MA (2004). "Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.". Biochem. Biophys. Res. Commun. 319 (1): 130–7. doi:10.1016/j.bbrc.2004.04.148. PMID 15158451.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wiltshire C, Gillespie DA, May GH (2005). "Sab (SH3BP5), a novel mitochondria-localized JNK-interacting protein.". Biochem. Soc. Trans. 32 (Pt 6): 1075–7. doi:10.1042/BST0321075. PMID 15506969.
- Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Beausoleil SA, Villén J, Gerber SA et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.