SFRS2

Serine/arginine-rich splicing factor 2
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsSRSF2 ; PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b
External IDsOMIM: 600813 MGI: 98284 HomoloGene: 37721 GeneCards: SRSF2 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez642720382
EnsemblENSG00000161547ENSMUSG00000034120
UniProtQ01130Q62093
RefSeq (mRNA)NM_001195427NM_011358
RefSeq (protein)NP_001182356NP_035488
Location (UCSC)Chr 17:
74.73 – 74.73 Mb
Chr 11:
116.85 – 116.85 Mb
PubMed search

Splicing factor, arginine/serine-rich 2 is a protein that in humans is encoded by the SFRS2 gene.[1][2][3]

Interactions

SFRS2 has been shown to interact with CDC5L[4] and ASF/SF2.[5]

References

  1. Bermingham JR Jr, Arden KC, Naumova AK, Sapienza C, Viars CS, Fu XD, Khotz J, Manley JL, Rosenfeld MG (February 1996). "Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2)". Genomics 29 (1): 70–9. doi:10.1006/geno.1995.1216. PMID 8530103.
  2. Fu XD, Maniatis T (May 1992). "Isolation of a complementary DNA that encodes the mammalian splicing factor SC35". Science 256 (5056): 535–8. doi:10.1126/science.1373910. PMID 1373910.
  3. "Entrez Gene: SFRS2 splicing factor, arginine/serine-rich 2".
  4. Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. (ENGLAND) 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529.
  5. Zhang, W J; Wu J Y (October 1996). "Functional properties of p54, a novel SR protein active in constitutive and alternative splicing". Mol. Cell. Biol. (UNITED STATES) 16 (10): 5400–8. ISSN 0270-7306. PMC 231539. PMID 8816452.

Further reading