Reticulocytopenia
Reticulocytopenia, or "aplastic crisis", is the medical term for an abnormal decrease of reticulocytes in the body. Reticulocytes are immature red blood cells. Reticulocytopenia may be a result of viral Parvovirus B19 infection, which invades and destroys red blood cell precursors and halts the red cell production. If infection occurs in individuals with sickle cell anemia[1] or spherocytosis, that will lead to incorporation of 2 anemia-induced mechanisms: decrease red cell production and hemolysis. The result is a severe anemia (aplastic crisis) which may require blood transfusion.
References
- ↑ "Sickle Cell Disease - Basic Principles and Clinical Practice" Edited by Stephen H. Embury, Robert P. Hebbel, Narla Mohandas and Martin Steinberg. Copyright 1996 by Lippincott-Raven. Section IV p352.
|
---|
| Red blood cells | |
---|
| Coagulation/ coagulopathy | |
---|
| |
---|
| Description |
- Immune system
- Cells
- Physiology
- coagulation
- proteins
- granule contents
- colony-stimulating
- heme and porphyrin
|
---|
| Disease |
- Red blood cell
- Monocyte and granulocyte
- Neoplasms and cancer
- Histiocytosis
- Symptoms and signs
- Blood tests
|
---|
| Treatment |
- Transfusion
- Drugs
- thrombosis
- bleeding
- other
|
---|
|
|