Relative accessible surface area

Relative accessible surface area or relative accessibility of a protein residue is a measure of residue solvent exposure. It can be calculated by formula:
RelAcc = 100 * Acc / MaxAcc [1]
where Acc is the solvent accessible surface area and MaxAcc is the maximum possible solvent accessible surface area for the residue in {\AA}^2 .
Maximum possible solvent accessible surface area for each Amino acid can be taken from the table below

[2]
Amino acid code Maximum solvent accessible surface
A 106
B 160
C 135
D 163
E 194
F 197
G 84
H 184
I 169
K 205
L 164
M 188
N 157
P 136
Q 198
R 248
S 130
T 142
V 142
W 227
X 180
Y 222
Z 196

where B stands for D or N; Z for E or Q and X for an undetermined Amino acid.

References

Notes

  1. ↑ Hyunsoo, Park; Haesun. "Prediction of Protein Relative Solvent Accessibility with Support Vector Machines and Long-range Interaction 3D Local Descriptor". Retrieved 10 April 2015.
  2. ↑ Rost, Burkhard; Sander, Chris (November 1994). "Conservation and Prediction of Solvent Accessibility in Protein Families". Proteins 20 (Conservation and Prediction of Solvent Accessibility in Protein Families): 218. PMID 7892171. Retrieved 10 April 2015.