RUFY1
| RUN and FYVE domain containing 1 | |||||||||||||
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 Rendering based on PDB 2YQM. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | RUFY1 ; RABIP4; ZFYVE12 | ||||||||||||
| External IDs | OMIM: 610327 MGI: 2429762 HomoloGene: 23522 GeneCards: RUFY1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 80230 | 216724 | |||||||||||
| Ensembl | ENSG00000176783 | ENSMUSG00000020375 | |||||||||||
| UniProt | Q96T51 | Q8BIJ7 | |||||||||||
| RefSeq (mRNA) | NM_001040451 | NM_172557 | |||||||||||
| RefSeq (protein) | NP_001035541 | NP_766145 | |||||||||||
| Location (UCSC) | Chr 5: 178.98 – 179.04 Mb | Chr 11: 50.39 – 50.43 Mb | |||||||||||
| PubMed search | |||||||||||||
RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene.[1][2] It is named after the RUN and FYVE domains it contains.
Interactions
RUFY1 has been shown to interact with BMX.[1]
References
- ↑ 1.0 1.1 Yang J, Kim O, Wu J, Qiu Y (Aug 2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking". J. Biol. Chem. 277 (33): 30219–26. doi:10.1074/jbc.M111933200. PMID 11877430.
- ↑ "Entrez Gene: RUFY1 RUN and FYVE domain containing 1".
Further reading
- Cormont M, Mari M, Galmiche A, Hofman P, Le Marchand-Brustel Y (2001). "A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic". Proc. Natl. Acad. Sci. U.S.A. 98 (4): 1637–42. doi:10.1073/pnas.031586998. PMC 29309. PMID 11172003.
- Fouraux MA, Deneka M, Ivan V, van der Heijden A, Raymackers J, van Suylekom D et al. (2004). "Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes". Mol. Biol. Cell 15 (2): 611–24. doi:10.1091/mbc.E03-05-0343. PMC 329268. PMID 14617813.
- Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.