RTI-171
RTI-171|
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| Systematic (IUPAC) name |
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3-methyl-5-[(1S,3S,4S,5R)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-4-yl]-1,2-oxazole |
| Clinical data |
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| Identifiers |
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| PubChem |
CID 10565888 |
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| Chemical data |
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| Formula |
C19H24N2O |
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296.406 g/mol |
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SMILES
- CN2C1CCC2CC(c(cc4)ccc4C)C1c3cc(C)no3
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 Y (what is this?) (verify) |
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(–)-2β-(3-Methylisoxazol-5-yl)-3β-(p-tolyl)tropane (RTI-171) is a phenyltropane derivative which acts as a selective dopamine reuptake inhibitor, with a relatively slow onset of action and short duration of effects found in animal studies.[1]
See also
References
- ↑ Kimmel HL, Carroll FI, Kuhar MJ (December 2001). "Locomotor stimulant effects of novel phenyltropanes in the mouse". Drug and Alcohol Dependence 65 (1): 25–36. doi:10.1016/S0376-8716(01)00144-2. PMID 11714587.
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| | 2-Carboxymethyl Esters | |
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| | (3,4-Disubstituted Phenyl)-tropanes | |
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| | Arylcarboxy | |
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| | Carboxyalkyl | |
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| | Acyl | |
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| | β,α Stereochemistry | |
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| | α,β Stereochemistry | |
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| | Heterocycles: 3-Substituted-isoxazol-5-yl | |
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| | Heterocycles: 3-Substituted-1,2,4-oxadiazole | |
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| | N-alkyl | |
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| | N-replaced (S,O,C) | |
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| | Irreversible | |
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| | Nortropanes (N-demethylated) | |
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- Agonists: Adamantanes: Amantadine
- Memantine
- Rimantadine; Aminotetralins: 7-OH-DPAT
- 8-OH-PBZI
- Rotigotine
- UH-232; Benzazepines: 6-Br-APB
- Fenoldopam
- SKF-38,393
- SKF-77,434
- SKF-81,297
- SKF-82,958
- SKF-83,959; Ergolines: Bromocriptine
- Cabergoline
- Dihydroergocryptine
- Epicriptine
- Lisuride
- LSD
- Pergolide; Dihydrexidine derivatives: 2-OH-NPA
- A-86929
- Adrogolide (ABT-431, DAS-431)
- Ciladopa
- Dihydrexidine
- Dinapsoline
- Dinoxyline
- Doxanthrine; Others: A-68930
- A-77636
- A-412997
- ABT-670
- ABT-724
- Aplindore
- Apomorphine
- Aripiprazole
- Bifeprunox
- BP-897
- Captodiame
- CY-208,243
- Dizocilpine
- Etilevodopa
- Flibanserin
- Ketamine
- Melevodopa
- Modafinil
- Pardoprunox
- Phencyclidine
- PD-128,907
- PD-168,077
- PF-219,061
- Piribedil
- Pramipexole
- Propylnorapomorphine
- Pukateine
- Quinagolide
- Quinelorane
- Quinpirole
- RDS-127
- Ro10-5824
- Ropinirole
- Rotigotine
- Roxindole
- Salvinorin A
- SKF-89,145
- Sumanirole
- Terguride
- Umespirone
- WAY-100,635
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| Others |
- Activity enhancers: BPAP
- PPAP; Levodopa prodrugs: XP21279
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