RPS9

Ribosomal protein S9

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
3J3A

Identifiers

Symbols

RPS9 ; S9

External IDs

OMIM: 603631 MGI: 1924096 HomoloGene: 68145 GeneCards: RPS9 Gene

Gene ontology
Molecular function	• structural constituent of ribosome • protein binding • rRNA binding • poly(A) RNA binding • translation regulator activity
Cellular component	• nucleus • nucleolus • cytoplasm • cytosol • ribosome • membrane • cytosolic small ribosomal subunit • ribonucleoprotein complex • extracellular vesicular exosome
Biological process	• nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • translation • translational initiation • translational elongation • translational termination • regulation of translation • SRP-dependent cotranslational protein targeting to membrane • positive regulation of cell proliferation • gene expression • viral process • RNA metabolic process • mRNA metabolic process • viral life cycle • viral transcription • cellular protein metabolic process
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 19:
54.2 – 54.25 Mb

Chr 7:
3.7 – 3.71 Mb

PubMed search

40S ribosomal protein S9 is a protein that in humans is encoded by the RPS9 gene.^[1]^[2]^[3]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome.^[3]

References

↑ Frigerio JM, Dagorn JC, Iovanna JL (Jul 1995). "Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs". Biochim Biophys Acta 1262 (1): 64–8. doi:10.1016/0167-4781(95)00045-i. PMID 7772601.
↑ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
↑ 3.0 3.1 "Entrez Gene: RPS9 ribosomal protein S9".

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Yu Y, Ji H, Doudna JA, Leary JA (2005). "Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes.". Protein Sci. 14 (6): 1438–46. doi:10.1110/ps.041293005. PMC 2253395. PMID 15883184.
Tu LC, Yan X, Hood L, Lin B (2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells.". Mol. Cell Proteomics 6 (4): 575–88. doi:10.1074/mcp.M600249-MCP200. PMID 17220478.
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RPS9

References

Further reading