RBM12
| RNA binding motif protein 12 | |||||||||||||
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 PDB rendering based on 1wel. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | RBM12 ; HRIHFB2091; SWAN | ||||||||||||
| External IDs | OMIM: 607179 MGI: 1922960 HomoloGene: 34993 GeneCards: RBM12 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10137 | 75710 | |||||||||||
| Ensembl | ENSG00000244462 | ENSMUSG00000089824 | |||||||||||
| UniProt | Q9NTZ6 | Q8R4X3 | |||||||||||
| RefSeq (mRNA) | NM_001198838 | NM_029397 | |||||||||||
| RefSeq (protein) | NP_001185767 | NP_083673 | |||||||||||
| Location (UCSC) | Chr 20: 35.65 – 35.66 Mb | Chr 2: 156.09 – 156.11 Mb | |||||||||||
| PubMed search | |||||||||||||
RNA-binding protein 12 is a protein that in humans is encoded by the RBM12 gene.[1][2]
This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 20q11.21. Alternative splicing in the 5' UTR results in two transcript variants. Both variants encode the same protein.[2]
References
- ↑ Stover C, Gradl G, Jentsch I, Speicher MR, Wieser R, Schwaeble W (Jul 2001). "cDNA cloning, chromosome assignment, and genomic structure of a human gene encoding a novel member of the RBM family". Cytogenet Cell Genet 92 (3-4): 225–30. doi:10.1159/000056908. PMID 11435693.
- ↑ 2.0 2.1 "Entrez Gene: RBM12 RNA binding motif protein 12".
Further reading
- Nakajima D, Okazaki N, Yamakawa H et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Olsen JV, Blagoev B, Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Kofler M, Motzny K, Freund C (2006). "GYF domain proteomics reveals interaction sites in known and novel target proteins.". Mol. Cell Proteomics 4 (11): 1797–811. doi:10.1074/mcp.M500129-MCP200. PMID 16120600.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Brill LM, Salomon AR, Ficarro SB et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC 187542. PMID 12421765.
- Deloukas P, Matthews LH, Ashurst J et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
- Nagase T, Ishikawa K, Suyama M et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
- Ueki N, Oda T, Kondo M et al. (1999). "Selection system for genes encoding nuclear-targeted proteins.". Nat. Biotechnol. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615.
External links
- RBM12 human gene location in the UCSC Genome Browser.
- RBM12 human gene details in the UCSC Genome Browser.
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