RAB3C

RAB3C, member RAS oncogene family

Identifiers

External IDs

OMIM: 612829 MGI: 1914545 HomoloGene: 23420 GeneCards: RAB3C Gene

Gene ontology
Molecular function	• GTP binding
Cellular component	• cytosol • plasma membrane • synaptic vesicle • vesicle • perinuclear region of cytoplasm
Biological process	• small GTPase mediated signal transduction • protein transport • regulation of exocytosis • antigen processing and presentation
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

ENSG00000152932

ENSMUSG00000021700

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 5:
57.88 – 58.16 Mb

Chr 13:
110.05 – 110.28 Mb

PubMed search

Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene.^[1]^[2]

References

↑ Cheng H, Ma Y, Ni X, Jiang M, Luo Y, Ying K, Xie Y, Ma Y (Sep 2002). "Cloning, mapping, and characterization of the human Rab3C gene". Biochem Genet 40 (7–8): 263–272. doi:10.1023/A:1019834901190. PMID 12296628.
↑ "Entrez Gene: RAB3C RAB3C, member RAS oncogene family".

Further reading

Gerhard DS; Wagner L; Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Matsumoto M; Miki T; Shibasaki T et al. (2004). "Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells". Proc. Natl. Acad. Sci. U.S.A. 101 (22): 8313–8318. doi:10.1073/pnas.0306709101. PMC 420391. PMID 15159548.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–15380. doi:10.1074/jbc.M212341200. PMID 12578829.
Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Schlüter OM, Khvotchev M, Jahn R, Südhof TC (2002). "Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion". J. Biol. Chem. 277 (43): 40919–40929. doi:10.1074/jbc.M203704200. PMID 12167638.
Uphues I, Chern Y, Eckel J (1996). "Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats". FEBS Lett. 377 (2): 109–112. doi:10.1016/0014-5793(95)01315-6. PMID 8543030.