Pyronaridine

Pyronaridine
Systematic (IUPAC) name

4-[(7-chloro-2-methoxy-pyrido[3,2-b]quinolin-10-yl)amino]-2,6-bis(pyrrolidin-1-ylmethyl)phenol
Clinical data
Legal status	CLP (EU): Acute Tox. 3(H301), Eye Dam. 1 (H318), Repr. 2 (H361), Aquatic Chronic 4 (H413)
Routes of administration	Oral, intramuscular injection, intravenous therapy
Identifiers
CAS Registry Number	74847-35-1^N
ATC code	None
PubChem	CID 5485198
ChemSpider	10647812^Y
UNII	TD3P7Q3SG6^Y
ChEMBL	CHEMBL35228^Y
Chemical data
Formula	C₂₉H₃₂Cl N₅O₂
Molecular mass	518.05 g/mol
SMILES Clc1ccc6c(c1)nc2ccc(OC)nc2c6Nc5cc(CN3CCCC3)c(O)c(CN4CCCC4)c5
InChI InChI=1S/C29H32ClN5O2/c1-37-26-9-8-24-28(33-26)27(23-7-6-21(30)16-25(23)32-24)31-22-14-19(17-34-10-2-3-11-34)29(36)20(15-22)18-35-12-4-5-13-35/h6-9,14-16,36H,2-5,10-13,17-18H2,1H3,(H,31,32) ^Y Key:DJUFPMUQJKWIJB-UHFFFAOYSA-N ^Y
N (what is this?) (verify)

Pyronaridine is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s. It was first assayed by Adegoke and Babalola in 2006.^[1]

It is one of the components of Pyramax.

References

↑ Chang C, Lin-Hua T, Jantanavivat C (1992). "Studies on a new antimalarial compound: pyronaridine". Trans R Soc Trop Med Hyg 86 (1): 7–10. doi:10.1016/0035-9203(92)90414-8. PMID 1566313.

Adegoke & Babalola 2006