Pyridoxal

Pyridoxal
Names
IUPAC name
3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde
Identifiers
66-72-8 Yes
65-22-5 (hydrochloride) 
ChEBI CHEBI:17310 Yes
ChEMBL ChEMBL102970 Yes
ChemSpider 1021 Yes
DrugBank DB00147 Yes
Jmol-3D images Image
KEGG C00250 Yes
PubChem 1050
UNII 3THM379K8A Yes
Properties
C8H9NO3
Molar mass 167.16 g/mol
Melting point 165 °C (329 °F; 438 K) (decomposes)
Related compounds
Related arylformaldehydes
Damnacanthal

Gossypol

Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Pyridoxal is one form of vitamin B6.

Some medically relevant bacteria, such as those in the genera Granulicatella and Abiotrophia, require pyridoxal for growth. This nutritional requirement can lead to the culture phenomenon of satellite growth. In in vitro culture, these pyridoxal-dependent bacteria may only grow in areas surrounding colonies of bacteria from other genera ("satellitism") that are capable of producing pyridoxal.

Pyridoxal is involved in what is believed to be the most ancient reaction of aerobic metabolism on Earth, about 2.9 billion years ago, a forerunner of the Great Oxidation Event[1]

References

  1. "Protein Domain Structure Uncovers the Origin of Aerobic Metabolism and the Rise of Planetary Oxygen", Gustavo Caetano-Anolles et al., published in Structure; paper available from University of Illinois News Bureau, 2012.