Protoporphyrinogen IX

Protoporphyrinogen IX
Identifiers

CAS Registry Number	7412-77-3
MeSH	protoporphyrinogen
PubChem	1039
Properties
Chemical formula	C₃₄H₅₂N₄O₄
Molar mass	580.801 g/mol
	Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Y verify (what is: Y/N?)
Infobox references

Protoporphyrinogen IX is a precursor for protoporphyrin IX. See Porphyrins for the pathway and more information.

See also

Protoporphyrinogen oxidase

Types of tetrapyrroles

Bilanes
(Linear)

Phytobilins

Phytochromobilin

Phycobilins	Phycoerythrobilin Phycocyanobilin Phycourobilin Phycoviolobilin

Methylcobalamin
Adenosylcobalamin
Cyanocobalamin

Protoporphyrins	Protoporphyrin IX Heme (b, c, a, o) Zinc protoporphyrin Magnesium protoporphyrin

Phytoporphyrins	Chlorophyll c Protochlorophyllide

Reduced
porphyrins

Porphyrinogens	Uroporphyrinogen (I, III) Coproporphyrinogen (I, III) Protoporphyrinogen IX

Chlorins	Chlorophyllide (a, b) Chlorophyll (a, b) Phaeophytin (a, b) Bacteriochlorophyll c

Bacteriochlorins	Bacteriochlorophyll a

Isobacteriochlorins	Siroheme Sirohydrochlorin

Corphins	Cofactor F430

Index of biochemical families

Carbohydrates	Alcohols Glycoproteins Glycosides

Lipids	Eicosanoids Fatty acids intermediates Glycerides Phospholipids Sphingolipids Steroids

Nucleic acids	Constituents intermediates

Proteins	Amino acids intermediates

Other	Tetrapyrroles intermediates

Heme metabolic intermediates

Porphyrin biosynthesis

early mitochondrial:	D-Aminolevulinic acid

cytosolic:	Porphobilinogen Hydroxymethylbilane Uroporphyrinogen III Coproporphyrinogen III

late mitochondrial:	Protoporphyrinogen IX Protoporphyrin IX

Heme degradation
and excretion

Breakdown of heme

spleen:	Heme → Biliverdin → Bilirubin

blood:	Bilirubin+Albumin

liver:	Bilirubin diglucuronide

Intestine, excretion in feces

Kidney, excretion in urine

Urobilin

Index of cells from bone marrow

Description	Immune system Cells Physiology coagulation proteins granule contents colony-stimulating heme and porphyrin metabolism intermediates

Disease	Red blood cell Monocyte and granulocyte Neoplasms and cancer Histiocytosis Symptoms and signs eponymous Blood tests findings

Treatment	Transfusion Drugs thrombosis bleeding other