Propiconazole

Propiconazole^[1]

Names
IUPAC name 1-[ [2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole
Identifiers
CAS Registry Number	60207-90-1 Y
ChEBI	CHEBI:8489 Y
ChEMBL	ChEMBL560579 Y
ChemSpider	39402 Y
InChI InChI=1S/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3 Y Key: STJLVHWMYQXCPB-UHFFFAOYSA-N Y InChI=1/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3 Key: STJLVHWMYQXCPB-UHFFFAOYAJ
Jmol-3D images	Image
KEGG	C11121 Y
PubChem	43234
SMILES Clc1ccc(c(Cl)c1)C2(OCC(O2)CCC)Cn3ncnc3
UNII	142KW8TBSR Y
Properties
Chemical formula	C15H17Cl2N3O2
Molar mass	342.22038
Boiling point	180 °C (356 °F; 453 K) at 0.1 mmHg
Solubility in water	100 ppm at 20 °C
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Y verify (what is: Y/N?)
Infobox references

Propiconazole is a triazole fungicide, also known as a DMI, or demethylation inhibiting fungicide due to its binding with and inhibiting the 14-alpha demethylase enzyme from demethylating a precursor to ergosterol. Without this demethylation step, the ergosterols are not incorporated into the growing fungal cell membranes, and cellular growth is stopped.

Agriculture

Propiconazole is used agriculturally as a systemic fungicide on turfgrasses grown for seed and aesthetic or athletic value, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums and prunes.^[2] It is also used in combination with permethrin in formulations of wood preserver.^[3] Propiconazole is a mixture^[4] of four stereoisomers and was first developed in 1979 by Janssen Pharmaceutica.^[5]

References

External links

• Non-CCA Wood Preservatives: Guide to Selected Resources - National Pesticide Information Center
• Propiconazole in the Pesticide Properties DataBase (PPDB)