Proliferating angioendotheliomatosis

Proliferating angioendotheliomatosis
Classification and external resources
ICD-10 D21 or C83.3
ICD-O M96803/{{{2}}}

Proliferating angioendotheliomatosis has historically been divided into two groups, (1) a reactive, involuting type and (2) a malignant, rapidly fatal type.[1]:598

The reactive involuting type is uncommon and occurs in patients with various diseases including subacute bacterial endocarditis and end-stage atherosclerotic disease. Patients present with various skin lesions and rashes - mostly commonly on the thighs. Treatment aimed at the underlying condition hastens the resolution of the lesions.

The malignant type is an intravascular lymphoma, usually of the diffuse B-cell type. It progresses rapidly through involvement of multiple body systems and mortality occurs in less than a year from the initial diagnosis. The average age of patients newly diagnosed is 55 years. Currently the causative mechanism is unknown. In a few cases treatment with palliative chemotherapy has been effective.[1]:598

Classification

Proliferating angioendotheliomatosis may be divided into the following types:[2]

See also

References

  1. ↑ 1.0 1.1 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.