Preproenzyme

Preproenzyme refers to the pre- portion refers to a signal sequence (signal peptide) which directs the enzyme to a specific organelle or subcellular localization. The pro- portion indicates that the enzyme is present in an inactive form and requires modification (e.g. cleavage) for activation.

See also

• Protein precursor
• Zymogen

Sources

• Braun P, de Groot A, Bitter W, Tommassen J. 1998. Secretion of elastinolytic enzymes and their propeptides by Pseudomonas aeruginosa. J Bacteriol. 1998; 180(13):3467-9. PMID 9642203