Prenylamine

Prenylamine

Systematic (IUPAC) name
(RS)-N-(1-methyl-2-phenylethyl)-3,3-diphenylpropan-1-amine
Clinical data
Legal status	Uncontrolled
Routes of administration	Oral
Identifiers
CAS Registry Number	390-64-7 N
ATC code	C01DX02
PubChem	CID 9801
ChemSpider	9418 N
UNII	K2OH82Z000 N
ChEMBL	CHEMBL24072 N
Synonyms	N-(3,3-diphenylpropyl)amphetamine
Chemical data
Formula	C24H27N
Molecular mass	329.48 g/mol
SMILES CC(Cc1ccccc1)NCCC(c2ccccc2)c3ccccc3
InChI InChI=1S/C24H27N/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,20,24-25H,17-19H2,1H3  N Key:IFFPICMESYHZPQ-UHFFFAOYSA-N  N
N (what is this?)  (verify)

Prenylamine (Segontin) is a calcium channel blocker of the amphetamine chemical class which is used as a vasodilator in the treatment of angina pectoris. It has been shown to partially metabolize to amphetamine and can cause false positives for it in drug tests.^[1][2][3] Prenylamine also appears to act as a vesicular monoamine transporter inhibitor, and has been demonstrated to deplete vesicular monoamine neurotransmitter stores similarly to reserpine.^[4]

See also

• Prenylation, or isoprenylation is the attachment of prenyl groups (3-methyl-but-2-en-1-yl) to cell membranes. Prenyl groups have been shown to be important for protein-protein binding through specialized prenyl-binding domains.

References