Pneumatosis intestinalis

Pneumatosis intestinalis

Micrograph showing large bowel wall with pneumatosis cystoides intestinalis, a generally benign subset of pneumatosis intestinalis. H&E stain.
Classification and external resources
ICD-10 K63.8, R93.3
ICD-9 569.89
DiseasesDB 31855
eMedicine article/371955

Pneumatosis intestinalis is a radiological sign which is highly suggestive for necrotizing enterocolitis. Pneumatosis intestinalis refers to gas cysts in the bowel wall.[1] This is in contrast to gas in the intestinal lumen. In newborns, pneumatosis intestinalis is considered diagnostic for necrotizing enterocolitis, and the air is produced by bacteria in the bowel wall.[2] The pathogenesis of pneumatosis intestinalis is poorly understood and is likely multifactorial. PI itself is not a disease, but rather a clinical sign. In some cases, PI is an incidental finding, whereas in others, it portends a life-threatening intra-abdominal condition.

References

  1. Braumann C, Menenakos C, Jacobi CA (2005). "Pneumatosis intestinalis--a pitfall for surgeons?". Scand J Surg 94 (1): 47–50. PMID 15865117.
  2. Skelley, Tao Le, Vikas Bhushan, Nathan William. First aid for the USMLE step 2 CK (8th ed. ed.). New York: McGraw-Hill Medical. pp. 369–370. ISBN 9780071761376.