Phosphinothricin acetyltransferase
| Phosphinothricin acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.183 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Phosphinothricin acetyltransferase (EC 2.3.1.183, PAT, PPT acetyltransferase, Pt-N-acetyltransferase, ac-Pt) is an enzyme with system name acetyl-CoA:phosphinothricin N-acetyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- acetyl-CoA + phosphinothricin
CoA + N-acetylphosphinothricin
The substrate phosphinothricin is used as a nonselective herbicide and is a potent inhibitor of EC 6.3.1.2.
References
- ↑ Botterman, J., Gosselé, V., Thoen, C. and Lauwereys, M. (1991). "Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins". Gene 102: 33–37. doi:10.1016/0378-1119(91)90534-i. PMID 1864506.
- ↑ Dröge-Laser, W., Siemeling, U., Pühler, A. and Broer, I. (1994). "The metabolites of the herbicide L-phosphinothricin (glufosinate) (identification, stability, and mobility in transgenic, herbicide-resistant, and untransformed plants)". Plant Physiol. 105: 159–166. PMID 12232195.
External links
- Phosphinothricin acetyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)