Phenindione

Phenindione
Systematic (IUPAC) name

2-phenyl-1H-indene-1,3(2H)-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy category	AU: D Passes into breast milk
Routes of administration	Oral
Pharmacokinetic data
Protein binding	88%
Half-life	5 to 10 hours
Identifiers
CAS Registry Number	83-12-5^Y
ATC code	B01AA02
PubChem	CID 4760
DrugBank	DB00498^Y
ChemSpider	4596^Y
UNII	5M7Y6274ZE^Y
KEGG	D08354^Y
ChEBI	CHEBI:8066^Y
ChEMBL	CHEMBL711^Y
Chemical data
Formula	C₁₅H₁₀O₂
Molecular mass	222.239 g/mol
SMILES O=C2c1ccccc1C(=O)C2c3ccccc3
InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H ^Y Key:NFBAXHOPROOJAW-UHFFFAOYSA-N ^Y
Y (what is this?) (verify)

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Hypersensitivity has been observed.^[1]

References

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Prostaglandin analogue (PGI2)	Beraprost Iloprost Prostacyclin Treprostinil

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Thromboxane inhibitors	Thromboxane synthase inhibitors Dipyridamole (+Aspirin) Picotamide Receptor antagonists Terutroban^†

Phosphodiesterase inhibitors	Cilostazol Dipyridamole Triflusal

Other	Cloricromen Ditazole Vorapaxar

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	Low molecular weight heparin Bemiparin Certoparin Dalteparin Enoxaparin Nadroparin Parnaparin Reviparin Tinzaparin^‡ Oligosaccharides Fondaparinux Idraparinux^§ Heparinoids Danaparoid Dermatan sulfate Sulodexide

Direct Xa inhibitors	Xabans Apixaban Betrixaban^§ Darexaban^§ Edoxaban Otamixaban^§ Rivaroxaban

Other

Index of cells from bone marrow

Description	Immune system Cells Physiology coagulation proteins granule contents colony-stimulating heme and porphyrin metabolism intermediates

Disease	Red blood cell Monocyte and granulocyte Neoplasms and cancer Histiocytosis Symptoms and signs eponymous Blood tests findings

Treatment	Transfusion Drugs thrombosis bleeding other