Phenampromide

Phenampromide

Systematic (IUPAC) name
N-(1-methyl-2-piperidin-1-ylethyl)-N-phenylpropanamide
Clinical data
Legal status	AU: Prohibited (S9)
Identifiers
CAS Registry Number	129-83-9 N
ATC code	None
PubChem	CID 8523
ChemSpider	16735960 Y
UNII	0600L2M6EZ Y
Chemical data
Formula	C17H26N2O
Molecular mass	274.40 g/mol
SMILES CCC(N(C1=CC=CC=C1)[C@@H](CN2CCCCC2)C)=O
InChI InChI=1S/C17H26N2O/c1-3-17(20)19(16-10-6-4-7-11-16)15(2)14-18-12-8-5-9-13-18/h4,6-7,10-11,15H,3,5,8-9,12-14H2,1-2H3/t15-/m1/s1  Y Key:DHTRHEVNFFZCNU-OAHLLOKOSA-N  Y
N (what is this?)  (verify)

Phenampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram and diampromide. It was invented in the 1960s^[1] by American Cyanamid Co.^[2] Although never given a general release, it was trialled and 50mg codeine ≈ 60mg phenampromide. Tests on the 2 isomers showed that all of the analgesic effects were caused by the (S) isomer.

Phenampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

References