Peruvoside

Peruvoside
Systematic (IUPAC) name
(3β,5β,8ξ,9ξ)- 3-[(6-deoxy- 3-O-methyl- α-D- glycero- hexopyranosyl)oxy]- 14-hydroxy- 19-oxocard- 20(22)enolide
Clinical data
Identifiers
1182-87-2 
C01AX02
PubChem CID 14449
ChemSpider 16498835 Yes
ChEMBL CHEMBL1075790 Yes
Synonyms (3S,5R,10R,13R,14S,17R)- 3-[(2S,5R)- 3,5-dihydroxy- 4-methoxy- 6-methyloxan- 2-yl]oxy- 14-hydroxy- 13-methyl- 17-(5-oxo-2H-furan-3-yl)- 1,2,3,4,5,6,7,8,9,11,12,15,16,17- tetradecahydrocyclopenta[a]phenanthrene- 10-carbaldehyde
Chemical data
Formula C30H44O9
548.665 g/mol
  (what is this?)  (verify)

Peruvoside (or cannogenin thevetoside) is a cardiac glycoside[1] for heart failure.[2]

It is derived from Cascabela thevetia (Thevetia neriifolia).[2]

References

  1. ↑ Arora, R. B.; Rangaswami, S. (1972). Peruvoside and Other Cardiotonic Glycoside[s] of Thevetia neriifolia Juss: Chemical, Pharmacological, and Clinical Studies. New Delhi, India: Thomson. LCCN 78900408.
  2. ↑ 2.0 2.1 Bhatia, M. L.; Manchanda, S. C.; Roy, S. B. (1970). "Haemodynamic Studies with Peruvoside in Human Congestive Heart Failure". British Medical Journal 3 (5725): 740–743. doi:10.1136/bmj.3.5725.740. PMC 1701679. PMID 4919553.