Papuamide

Papuamides A and B are depsipeptides which appear to protect T cells from HIV.^[1] They were isolated from the sponge Theonella,^[1] and are part of a larger group of structurally similar depsipeptides—also isolated from sponges—including neamphamide A, callipeltin A, and mirabamides A-D.^[2]

References

1. ↑ 1.0 1.1 Ford PW, Gustafson KR, McKee TC, Shigematsu N, Maurizi LK, Pannell LK, Williams DE, de Silva ED, Lassota P, Allen TM, Van Soest R, Andersen RJ, Boyd MR. Papuamides A-D, HIV-Inhibitory and Cytotoxic Depsipeptides from the Sponges Theonella mirabilis and Theonella swinhoei Collected in Papua New Guinea. J. Am. Chem. Soc. 1999;121:5899–5909
2. ↑ Andjelic CD, Planelles V, Barrows LR. Characterizing the Anti-HIV Activity of Papuamide A. Mar Drugs. 2008;6(4):528-49