PTPN5
Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the gene.[1][2]
References
Further reading
- Kanamaru H, Asahina K (1991). "[Venous aneurysm of V. saphena accessoria--a case report]". Nippon Geka Gakkai zasshi 91 (10): 1648–51. PMID 2263249.
- Li X, Luna J, Lombroso PJ, Francke U (1996). "Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci". Genomics 28 (3): 442–9. doi:10.1006/geno.1995.1173. PMID 7490079.
- Yoneya T; Yamada Y; Kakeda M et al. (1997). "Molecular cloning of a novel receptor-type protein tyrosine phosphatase from murine fetal liver". Gene 194 (2): 241–7. doi:10.1016/S0378-1119(97)00174-1. PMID 9272866.
- Pulido R, Zúñiga A, Ullrich A (1999). "PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif". EMBO J. 17 (24): 7337–50. doi:10.1093/emboj/17.24.7337. PMC 1171079. PMID 9857190.
- Nguyen TH, Liu J, Lombroso PJ (2002). "Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420". J. Biol. Chem. 277 (27): 24274–9. doi:10.1074/jbc.M111683200. PMID 11983687.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Eswaran J; von Kries JP; Marsden B et al. (2006). "Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases". Biochem. J. 395 (3): 483–91. doi:10.1042/BJ20051931. PMC 1462698. PMID 16441242.
PDB gallery |
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| | 2bij: CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP, STRIATUM ENRICHED ENRICHED PHOSPHATASE) |
| 2bv5: CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 AT 1.8A RESOLUTION |
| 2cjz: CRYSTAL STRUCTURE OF THE C472S MUTANT OF HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP, STRIATUM ENRICHED PHOSPHATASE) IN COMPLEX WITH PHOSPHOTYROSINE |
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