PSKH1
| Protein serine kinase H1 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbol | PSKH1 | ||||||||||||
| External IDs | OMIM: 177015 MGI: 3528383 HomoloGene: 48461 IUPHAR: 2178 GeneCards: PSKH1 Gene | ||||||||||||
| EC number | 2.7.11.1 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 5681 | 244631 | |||||||||||
| Ensembl | ENSG00000159792 | ENSMUSG00000048310 | |||||||||||
| UniProt | P11801 | Q91YA2 | |||||||||||
| RefSeq (mRNA) | NM_006742 | NM_173432 | |||||||||||
| RefSeq (protein) | NP_006733 | NP_775608 | |||||||||||
| Location (UCSC) | Chr 16: 67.93 – 67.96 Mb | Chr 8: 105.9 – 105.93 Mb | |||||||||||
| PubMed search | |||||||||||||
Serine/threonine-protein kinase H1 is an enzyme that in humans is encoded by the PSKH1 gene.[1][2]
Interactions
PSKH1 has been shown to interact with CDC6.[3]
References
- ↑ Larsen F, Solheim J, Kristensen T, Kolstø AB, Prydz H (Feb 1994). "A tight cluster of five unrelated human genes on chromosome 16q22.1". Hum Mol Genet 2 (10): 1589–95. doi:10.1093/hmg/2.10.1589. PMID 8268911.
- ↑ "Entrez Gene: PSKH1 protein serine kinase H1".
- ↑ Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K (Jan 1999). "Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization". EMBO J. 18 (2): 396–410. doi:10.1093/emboj/18.2.396. PMC 1171134. PMID 9889196.
Further reading
- Hanks SK (1987). "Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family.". Proc. Natl. Acad. Sci. U.S.A. 84 (2): 388–92. doi:10.1073/pnas.84.2.388. PMC 304212. PMID 2948189.
- Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K (1999). "Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.". EMBO J. 18 (2): 396–410. doi:10.1093/emboj/18.2.396. PMC 1171134. PMID 9889196.
- Amarzguioui M, Brede G, Babaie E, Grotli M, Sproat B, Prydz H (2000). "Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes.". Nucleic Acids Res. 28 (21): 4113–24. doi:10.1093/nar/28.21.4113. PMC 113158. PMID 11058107.
- Brede G, Solheim J, Tröen G, Prydz H (2001). "Characterization of PSKH1, a novel human protein serine kinase with centrosomal, golgi, and nuclear localization.". Genomics 70 (1): 82–92. doi:10.1006/geno.2000.6365. PMID 11087665.
- Brede G, Solheim J, Prydz H (2002). "PSKH1, a novel splice factor compartment-associated serine kinase.". Nucleic Acids Res. 30 (23): 5301–9. doi:10.1093/nar/gkf648. PMC 137962. PMID 12466556.
- Brede G, Solheim J, Stang E, Prydz H (2004). "Mutants of the protein serine kinase PSKH1 disassemble the Golgi apparatus.". Exp. Cell Res. 291 (2): 299–312. doi:10.1016/j.yexcr.2003.07.009. PMID 14644153.