PPP4R1
| Protein phosphatase 4, regulatory subunit 1 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | PPP4R1 ; MEG1; PP4(Rmeg); PP4R1 | ||||||||||||
| External IDs | OMIM: 604908 HomoloGene: 81737 GeneCards: PPP4R1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 9989 | 70351 | |||||||||||
| Ensembl | ENSG00000154845 | ENSMUSG00000061950 | |||||||||||
| UniProt | Q8TF05 | Q8K2V1 | |||||||||||
| RefSeq (mRNA) | NM_001042388 | NM_001114131 | |||||||||||
| RefSeq (protein) | NP_001035847 | NP_001107603 | |||||||||||
| Location (UCSC) | Chr 18: 9.55 – 9.62 Mb | Chr 17: 65.78 – 65.84 Mb | |||||||||||
| PubMed search | |||||||||||||
Serine/threonine-protein phosphatase 4 regulatory subunit 1 is an enzyme that in humans is encoded by the PPP4R1 gene.[1][2]
Interactions
PPP4R1 has been shown to interact with PPP4C.[3][4][5]
References
- ↑ Kloeker S, Wadzinski BE (Mar 1999). "Purification and identification of a novel subunit of protein serine/threonine phosphatase 4". J Biol Chem 274 (9): 5339–47. doi:10.1074/jbc.274.9.5339. PMID 10026142.
- ↑ "Entrez Gene: PPP4R1 protein phosphatase 4, regulatory subunit 1".
- ↑ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- ↑ Chen, Ginny I; Tisayakorn Sally, Jorgensen Claus, D'Ambrosio Lisa M, Goudreault Marilyn, Gingras Anne-Claude (Oct 2008). "PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4". J. Biol. Chem. (United States) 283 (43): 29273–84. doi:10.1074/jbc.M803443200. ISSN 0021-9258. PMC 2662017. PMID 18715871.
- ↑ Gingras, Anne-Claude; Caballero Michael; Zarske Marcel; Sanchez Amy; Hazbun Tony R; Fields Stanley; Sonenberg Nahum; Hafen Ernst; Raught Brian; Aebersold Ruedi (Nov 2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Mol. Cell Proteomics (United States) 4 (11): 1725–40. doi:10.1074/mcp.M500231-MCP200. ISSN 1535-9476. PMID 16085932.
Further reading
- Ewing RM; Chu P; Elisma F et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Zhang X; Ozawa Y; Lee H et al. (2005). "Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4". Genes Dev. 19 (7): 827–39. doi:10.1101/gad.1286005. PMC 1074320. PMID 15805470.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Wada T; Miyata T; Inagi R et al. (2002). "Cloning and characterization of a novel subunit of protein serine/threonine phosphatase 4 from mesangial cells". J. Am. Soc. Nephrol. 12 (12): 2601–8. PMID 11729228.
- Yu W; Andersson B; Worley KC et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
- Andersson B; Wentland MA; Ricafrente JY et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.