PLSCR4
| Phospholipid scramblase 4 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | PLSCR4 ; TRA1 | ||||||||||||
| External IDs | OMIM: 607612 MGI: 2143267 HomoloGene: 23217 GeneCards: PLSCR4 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 57088 | 235527 | |||||||||||
| Ensembl | ENSG00000114698 | ENSMUSG00000032377 | |||||||||||
| UniProt | Q9NRQ2 | P58196 | |||||||||||
| RefSeq (mRNA) | NM_001128304 | NM_178711 | |||||||||||
| RefSeq (protein) | NP_001121776 | NP_848826 | |||||||||||
| Location (UCSC) | Chr 3: 145.91 – 145.97 Mb | Chr 9: 92.46 – 92.49 Mb | |||||||||||
| PubMed search | |||||||||||||
Phospholipid scramblase 4, also known as Ca2+-dependent phospholipid scramblase 4, is a protein that in humans is encoded by the PLSCR4 gene.[1][2]
See also
- scramblase
References
- ↑ "Entrez Gene: phospholipid scramblase 4".
- ↑ Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (July 2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta 1467 (1): 244–53. doi:10.1016/S0005-2736(00)00236-4. PMID 10930526.
Further reading
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Rose JE, Behm FM, Drgon T, et al.. "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.". Mol. Med. 16 (7-8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Shibata H, Suzuki H, Kakiuchi T, et al. (2008). "Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.". J. Biol. Chem. 283 (15): 9623–32. doi:10.1074/jbc.M800717200. PMID 18256029.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Sahu SK, Aradhyam GK, Gummadi SN (2009). "Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell.". Biochim. Biophys. Acta 1790 (10): 1274–81. doi:10.1016/j.bbagen.2009.06.008. PMID 19540310.
- Py B, Basmaciogullari S, Bouchet J, et al. (2009). "The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membrane.". PLoS ONE 4 (3): e5006. doi:10.1371/journal.pone.0005006. PMC 2659420. PMID 19333378.