PDZK1IP1

PDZK1 interacting protein 1
Identifiers
SymbolsPDZK1IP1 ; DD96; MAP17; SPAP
External IDsOMIM: 607178 MGI: 1914432 HomoloGene: 4213 GeneCards: PDZK1IP1 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez1015867182
EnsemblENSG00000162366ENSMUSG00000028716
UniProtQ13113Q9CQH0
RefSeq (mRNA)NM_005764NM_001164557
RefSeq (protein)NP_005755NP_001158029
Location (UCSC)Chr 1:
47.65 – 47.66 Mb		Chr 4:
115.09 – 115.09 Mb
PubMed search

PDZK1-interacting protein 1 is a protein that in humans is encoded by the PDZK1IP1 gene.[1][2][3][4][5]

Interactions

PDZK1IP1 has been shown to interact with PDZK1.[3][4][6]

References

  1. ↑ Kocher O, Cheresh P, Brown LF, Lee SW (Feb 1999). "Identification of a novel gene, selectively up-regulated in human carcinomas, using the differential display technique". Clin. Cancer Res. 1 (10): 1209–15. PMID 9815914. Check date values in: |year= / |date= mismatch (help)
  2. ↑ Kocher O, Cheresh P, Lee SW (Sep 1996). "Identification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth". Am. J. Pathol. 149 (2): 493–500. PMC 1865305. PMID 8701988.
  3. ↑ 3.0 3.1 Silver DL, Wang N, Vogel S (Jul 2003). "Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels". J. Biol. Chem. 278 (31): 28528–32. doi:10.1074/jbc.M304109200. PMID 12754212.
  4. ↑ 4.0 4.1 Pribanic S, Gisler SM, Bacic D, Madjdpour C, Hernando N, Sorribas V et al. (Sep 2003). "Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells". Am. J. Physiol. Renal Physiol. 285 (4): F784–91. doi:10.1152/ajprenal.00109.2003. PMID 12837682.
  5. ↑ "Entrez Gene: PDZK1IP1 PDZK1 interacting protein 1".
  6. ↑ Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA et al. (Nov 2003). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells". Kidney Int. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.

Further reading

  • Kocher O, Comella N, Tognazzi K, Brown LF (1998). "Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains". Lab. Invest. 78 (1): 117–25. PMID 9461128.
  • Göttgens B, Barton LM, Chapman MA, Sinclair AM, Knudsen B, Grafham D et al. (2002). "Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci". Genome Res. 12 (5): 749–59. doi:10.1101/gr.45502. PMC 186570. PMID 11997341. Vancouver style error (help)
  • Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA et al. (2003). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells". Kidney Int. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.
  • Guijarro MV, Castro ME, Romero L, Moneo V, Carnero A (2007). "Large scale genetic screen identifies MAP17 as protein bypassing TNF-induced growth arrest". J. Cell. Biochem. 101 (1): 112–21. doi:10.1002/jcb.21163. PMID 17230460.
  • Guijarro MV, Leal JF, Fominaya J, Blanco-Aparicio C, Alonso S, Lleonart M et al. (2007). "MAP17 overexpression is a common characteristic of carcinomas". Carcinogenesis 28 (8): 1646–52. doi:10.1093/carcin/bgm083. PMID 17426052.
  • Guijarro MV, Leal JF, Blanco-Aparicio C, Alonso S, Fominaya J, Lleonart M et al. (2007). "MAP17 enhances the malignant behavior of tumor cells through ROS increase". Carcinogenesis 28 (10): 2096–104. doi:10.1093/carcin/bgm124. PMID 17548903.

External links