PDLIM1

PDZ and LIM domain 1

PDB rendering based on 1x62.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsPDLIM1 ; CLIM1; CLP-36; CLP36; HEL-S-112; hCLIM1
External IDsOMIM: 605900 MGI: 1860611 HomoloGene: 9643 GeneCards: PDLIM1 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez912454132
EnsemblENSG00000107438ENSMUSG00000055044
UniProtO00151O70400
RefSeq (mRNA)NM_020992NM_016861
RefSeq (protein)NP_066272NP_058557
Location (UCSC)Chr 10:
97 – 97.05 Mb		Chr 19:
40.22 – 40.27 Mb
PubMed search

PDZ and LIM domain protein 1 is a protein that in humans is encoded by the PDLIM1 gene.[1][2]


Interactions

PDLIM1 has been shown to interact with:

References

  1. ↑ Kotaka M, Kostin S, Ngai S, Chan K, Lau Y, Lee SM et al. (October 2000). "Interaction of hCLIM1, an enigma family protein, with alpha-actinin 2". J Cell Biochem 78 (4): 558–65. doi:10.1002/1097-4644(20000915)78:4<558::AID-JCB5>3.0.CO;2-I. PMID 10861853.
  2. ↑ "Entrez Gene: PDLIM1 PDZ and LIM domain 1 (elfin)".
  3. ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  4. ↑ 4.0 4.1 Vallenius T, Luukko K, Mäkelä TP (April 2000). "CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4". J. Biol. Chem. 275 (15): 11100–5. doi:10.1074/jbc.275.15.11100. PMID 10753915. Vancouver style error (help)
  5. ↑ Bauer K, Kratzer M, Otte M, de Quintana KL, Hagmann J, Arnold GJ et al. (December 2000). "Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells". Blood 96 (13): 4236–45. PMID 11110697.
  6. ↑ 6.0 6.1 Johnsen SA, Güngör C, Prenzel T, Riethdorf S, Riethdorf L, Taniguchi-Ishigaki N et al. (January 2009). "Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer". Cancer Res. 69 (1): 128–36. doi:10.1158/0008-5472.CAN-08-1630. PMC 2713826. PMID 19117995. Vancouver style error (help)

Further reading

  • Wang H, Harrison-Shostak DC, Lemasters JJ, Herman B (1996). "Cloning of a rat cDNA encoding a novel LIM domain protein with high homology to rat RIL.". Gene 165 (2): 267–71. doi:10.1016/0378-1119(95)00542-E. PMID 8522188.
  • Kotaka M, Ngai SM, Garcia-Barcelo M, Tsui SK, Fung KP, Lee CY et al. (1999). "Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1).". J. Cell. Biochem. 72 (2): 279–85. doi:10.1002/(SICI)1097-4644(19990201)72:2<279::AID-JCB12>3.0.CO;2-7. PMID 10022510.
  • Vallenius T, Luukko K, Mäkelä TP (2000). "CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.". J. Biol. Chem. 275 (15): 11100–5. doi:10.1074/jbc.275.15.11100. PMID 10753915. Vancouver style error (help)
  • Bauer K, Kratzer M, Otte M, de Quintana KL, Hagmann J, Arnold GJ et al. (2001). "Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells.". Blood 96 (13): 4236–45. PMID 11110697.
  • Ostendorff HP, Peirano RI, Peters MA, Schlüter A, Bossenz M, Scheffner M et al. (2002). "Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors.". Nature 416 (6876): 99–103. doi:10.1038/416099a. PMID 11882901. Vancouver style error (help)
  • Vallenius T, Mäkelä TP (2003). "Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein.". J. Cell. Sci. 115 (Pt 10): 2067–73. PMID 11973348. Vancouver style error (help)
  • Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T et al. (2003). "Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.". Cell 111 (5): 673–85. doi:10.1016/S0092-8674(02)01084-X. PMID 12464179.
  • Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
  • Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
  • Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Miehe U, Kadyrov M, Neumaier-Wagner P, Bartz C, Rath W, Huppertz B (2007). "Expression of the actin stress fiber-associated protein CLP36 in the human placenta.". Histochem. Cell Biol. 126 (4): 465–71. doi:10.1007/s00418-006-0182-5. PMID 16609848.