Oxford Nanopore Technologies

Oxford Nanopore Technologies
Industry Nanopore sequencing
Founded 2005
Founder
Headquarters Oxford Science Park, Oxford, United Kingdom
Key people
  • Clive G. Brown (CTO)
  • Hagan Bayley
  • Jim McDonald (CFO)
  • John Milton (CSO)
  • Gordon Sanghera (CEO)
  • Spike Willcocks (VP)
Website www.nanoporetech.com

Oxford Nanopore Technologies Limited is a U.K.-based startup company which is developing nanopore sequencing platforms for the direct, electronic analysis of single molecules.[1][2][3][4]

Products under development include:

These products are intended to be used for the analysis of DNA, RNA, proteins and small molecules with a range of applications in personalized medicine, crop science, and scientific research.[2][6]

The company was founded in 2005 as a spin-out from the University of Oxford by Hagan Bayley, Gordon Sanghera, and Spike Willcocks, with seed funding from the IP Group.[7][8] As of 2014 the company had raised over £145 million in investment.[7]

As of February 2015, MinION is being tested in the MinION Access Programme (MAP), whereby a number of potential users is testing the product in research laboratories. PromethION and GridION have not yet been brought to market. In a paper published in November 2014, one of the MAP participants wrote, "The MinION is an exciting step in a new direction for single-molecule sequencing, though it will require dramatic decreases in error rates before it lives up to its promise."[2]

References

  1. ↑ Eisenstein, M. (2012). "Oxford Nanopore announcement sets sequencing sector abuzz". Nature Biotechnology 30 (4): 295. doi:10.1038/nbt0412-295. PMID 22491260.
  2. ↑ 2.0 2.1 2.2 2.3 Mikheyev, A. S.; Tin, M. M. Y. (2014). "A first look at the Oxford Nanopore MinION sequencer". Molecular Ecology Resources 14 (6): 1097–102. doi:10.1111/1755-0998.12324. PMID 25187008.
  3. ↑ Loman, N. J.; Quinlan, A. R. (2014). "Poretools: A toolkit for analyzing nanopore sequence data". Bioinformatics 30 (23): 3399–401. doi:10.1093/bioinformatics/btu555. PMID 25143291.
  4. ↑ Oxford Nanopore on Twitter
  5. ↑ Check Hayden, E. (2014). "Data from pocket-sized genome sequencer unveiled". Nature. doi:10.1038/nature.2014.14724.
  6. ↑ Check Hayden, E. (2012). "Nanopore genome sequencer makes its debut". Nature. doi:10.1038/nature.2012.10051.
  7. ↑ 7.0 7.1 "Company history". Oxford Nanopore Technologies.
  8. ↑ "DNA sequencing: The hole story". The Economist (London). 2008-10-16. Retrieved 2014-10-19.