Oxetorone

Oxetorone
Ball-and-stick model
Ball-and-stick model
Systematic (IUPAC) name
(3Z)-3-[1]benzofuro[3,2-c][1]benzoxepin-6(12H)-ylidene-N,N-dimethylpropan-1-amine
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
26020-55-3 Yes
N02CX06
PubChem CID 6436540
UNII T3XOS33TIQ Yes
KEGG D08312 Yes
Chemical data
Formula C21H21NO2
319.40 g/mol
 Yes (what is this?)  (verify)

Oxetorone (INN), as oxetorone fumarate (USAN) (brand names Nocertone, Oxedix), is a serotonin antagonist, antihistamine, and alpha blocker used as an antimigraine drug.[1][2][3][4]

Association with hyperprolactinemia has been described.[5]

References

  1. ↑ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1493–. ISBN 978-0-412-46630-4.
  2. ↑ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 2935–. ISBN 978-0-8155-1856-3.
  3. ↑ C.J. van Boxtel; B. Santoso; I.R. Edwards (6 August 2008). Drug Benefits and Risks: International Textbook of Clinical Pharmacology - Revised 2nd Edition. IOS Press. pp. 699–. ISBN 978-1-60750-345-3.
  4. ↑ Massiou H (2000). "[Prophylactic treatments of migraine]". Rev. Neurol. (Paris) (in French). 156 Suppl 4: 4S79–86. PMID 11139754.
  5. ↑ Pradalier A (December 1996). "Hyperprolactinaemia and depression induced by oxetorone". Cephalalgia 16 (8): 560–1. doi:10.1046/j.1468-2982.1996.1608560.x. PMID 8980859.