Otis (given name)

Otis Armstrong, a former NFL running back for the Denver Broncos
Otis R. Bowen, the former governor of Indiana and former United States Secretary of Health and Human Services
Otis Chandler, publisher of the Los Angeles Times between 1960 and 1980
Otis Gibson, Methodist missionary
Otis Grant, a professional boxer
Otis Jackson Jr., Hip Hop producer and rapper
Otis King, inventor
Otis Nixon, former Major League Baseball player
Otis Redding, musician
Otis Rush, bluesman
Otis A. Singletary, historian and university administrator
Otis Skinner, American actor
Otis Smith (basketball), American basketball player
Otis Smith (American football), American football player
Otis M. Smith, justice on the Michigan Supreme Court
Otis Spann, an American blues pianist
Otis Taylor (musician), an American blues musician
Otis Taylor (American football), a former American football player
Otis Williams, singer and co-founder of The Temptations

Fictional characters

Otis, a puppy in The Adventures of Milo and Otis
Otis the Aardvark, a BBC puppet character
Otis "Bad" Blake,the main character in Scott Cooper's 2009 film, Crazy Heart
Otis Campbell, the town drunk on The Andy Griffith Show
Otis the Cow, the main character in Nickelodeon's 2006 film, Barnyard, and its TV spin-off series, Back at the Barnyard
Otis B. Driftwood, a fictional character that has appeared in the Rob Zombie horror films House of 1000 Corpses and The Devil's Rejects taken from the character of the same name popularized by Groucho Marx
Otis, a fictional character in the movie Good Burger
Otis (Superman), an associate of Lex Luthor, in the films Superman and Superman II
Otis Otis, a vampire in Heather Brewer's teen book series The Chronicles of Vladimir Tod