OR51B4
| Olfactory receptor, family 51, subfamily B, member 4 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | OR51B4 ; HOR5'Beta1 | ||||||||||||
| External IDs | MGI: 1341906 HomoloGene: 88376 GeneCards: OR51B4 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 79339 | 18367 | |||||||||||
| Ensembl | ENSG00000183251 | ENSMUSG00000058200 | |||||||||||
| UniProt | Q9Y5P0 | n/a | |||||||||||
| RefSeq (mRNA) | NM_033179 | NM_013618 | |||||||||||
| RefSeq (protein) | NP_149419 | NP_038646 | |||||||||||
| Location (UCSC) | Chr 11: 5.32 – 5.32 Mb | Chr 7: 103.88 – 103.88 Mb | |||||||||||
| PubMed search | |||||||||||||
Olfactory receptor 51B4 is a protein that in humans is encoded by the OR51B4 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
Further reading
- Bulger M, van Doorninck JH, Saitoh N et al. (1999). "Conservation of sequence and structure flanking the mouse and human β-globin loci: The β-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828. PMID 10220430.
- Bulger M, Bender MA, van Doorninck JH et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse β-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958. PMID 11121057.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
External links
- OR51B4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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