OBSL1

Obscurin-like 1

PDB rendering based on 2cpc.

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
2CPC, 2E6P, 2E6Q, 2LU7, 2LVC, 2WP3, 2WWK, 2WWM, 3KNB

Identifiers

OBSL1 ; KIAA0657; MGC71026

External IDs

OMIM: 610991 HomoloGene: 28013 GeneCards: OBSL1 Gene

Gene ontology
Molecular function	• protein binding • cytoskeletal adaptor activity
Cellular component	• cytoplasm • Golgi apparatus • centrosome • intercalated disc • Z disc • M band • perinuclear region of cytoplasm • 3M complex
Biological process	• microtubule cytoskeleton organization • cytoskeleton organization • Golgi organization • regulation of mitosis • protein localization to Golgi apparatus • positive regulation of dendrite morphogenesis • cardiac myofibril assembly
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000124006

ENSMUSG00000026211

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 2:
220.42 – 220.44 Mb

Chr 1:
75.48 – 75.51 Mb

PubMed search

Obscurin-like protein 1 is a protein that in humans is encoded by the OBSL1 gene.^[1]^[2]

References

↑ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
↑ "Entrez Gene: OBSL1 obscurin-like 1".

Further reading

Nakajima D, Okazaki N, Yamakawa H et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Geisler SB, Robinson D, Hauringa M et al. (2007). "Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin.". Genomics 89 (4): 521–31. doi:10.1016/j.ygeno.2006.12.004. PMC 1885211. PMID 17289344.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu W, Andersson B, Worley KC et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

External links

PDB gallery

2cpc: Solution structure of RSGI RUH-030, an Ig like domain from human cDNA