Nolatrexed

Nolatrexed
Names

IUPAC name 2-Amino-6-methyl-5-(4-pyridylthio)-1H-quinazolin-4-one
Identifiers
CAS Registry Number	147149-76-6^Y
ChemSpider	97268
InChI InChI=1S/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19) Key: XHWRWCSCBDLOLM-UHFFFAOYSA-N InChI=1/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19) Key: XHWRWCSCBDLOLM-UHFFFAOYAK
Jmol-3D images	Image
PubChem	108189
SMILES CC1=C(C2=C(C=C1)NC(=NC2=O)N)SC3=CC=NC=C3
Properties
Chemical formula	C₁₄H₁₂N₄OS
Molar mass	284.34 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Y verify (what is: Y/N?)
Infobox references

Nolatrexed is a thymidylate synthase inhibitor.^[1]^[2]

References

↑ Hughes AN, Rafi I, Griffin MJ et al. (January 1999). "Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days". Clin. Cancer Res. 5 (1): 111–8. PMID 9918208.
↑ "Nolatrexed". PubChem.gov. Pub Chem. Retrieved 12 August 2014.