Nocardia farcinica
| Nocardia farcinica | |
|---|---|
| Scientific classification | |
| Kingdom: | Bacteria |
| Phylum: | Actinobacteria |
| Order: | Actinomycetales |
| Suborder: | Corynebacterineae |
| Family: | Nocardiaceae |
| Genus: | Nocardia |
| Species: | Nocardia farcinica |
Nocardia farcinica is a species of bacteria and a member of the genus Nocardia. This species is very similar in phenotype to Nocardia asteroides, to the degree that some isolates of N. asteroides were later found to be Nocardia farcinica.[1]
Pathogenicity
N. farcinica may be a causative agent of nocardiosis[2] or of secondary infections in immunocompromised patients.[3] Strains of this species have been isolated from human brain abscesses.[4]
Genome
N. farcinica contains a 6 million base pair genome with an average GC content of 70.8%. A sequenced strain, IFM 10152, is also known to contain two plasmids, pNF1 pNF2. The chromosome encodes 5,674 potential protein-coding open reading frames. This genome may have undergone numerous gene duplication events as a result of adapting to new environments.[5]
References
- ↑ Wallace RJ, Jr; Tsukamura, M; Brown, BA; Brown, J; Steingrube, VA; Zhang, YS; Nash, DR (December 1990). "Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica.". Journal of clinical microbiology 28 (12): 2726–32. PMC 268263. PMID 2280003.
- ↑ Holm, P (July 1975). "Seven cases of human nocardiosis caused by Nocardia farcinica.". Sabouraudia 13 (2): 161–9. doi:10.1080/00362177585190301. PMID 1162538.
- ↑ Torres, O. H.; Domingo, P.; Pericas, R.; Boiron, P.; Montiel, J. A.; Vázquez, G. (3 April 2000). "Infection Caused by Nocardia farcinica : Case Report and Review". European Journal of Clinical Microbiology & Infectious Diseases 19 (3): 205–212. doi:10.1007/s100960050460.
- ↑ Malincarne, Lisa; Marroni, Massimo; Farina, Claudio; Camanni, Guido; Valente, Marina; Belfiori, Barbara; Fiorucci, Stefano; Floridi, Piero; Cardaccia, Angela; Stagni, Giuliano (1 May 2002). "Primary brain abscess with Nocardia farcinica in an immunocompetent patient". Clinical Neurology and Neurosurgery 104 (2): 132–135. doi:10.1016/S0303-8467(01)00201-3.
- ↑ Ishikawa, J; Yamashita, A; Mikami, Y; Hoshino, Y; Kurita, H; Hotta, K; Shiba, T; Hattori, M (Oct 12, 2004). "The complete genomic sequence of Nocardia farcinica IFM 10152.". Proceedings of the National Academy of Sciences of the United States of America 101 (41): 14925–30. doi:10.1073/pnas.0406410101. PMC 522048. PMID 15466710.
Further reading
- Malla, Sailesh; Pandey, Ramesh Prasad; Kim, Byung-Gee; Sohng, Jae Kyung (22 April 2013). "Regiospecific modifications of naringenin for astragalin production in Escherichia coli". Biotechnology and Bioengineering 110 (9): 2525–2535. doi:10.1002/bit.24919.
- Toyomitsu, Sawai (April 8, 2014). "A case of community-acquired pneumonia due to influenza A virus and Nocardia farcinica co-infection". Journal of Infection and Chemotherapy 20 (8): 506–508. doi:10.1016/j.jiac.2014.04.008.