Nitarsone

Nitarsone
Names
IUPAC name
(4-Nitrophenyl)arsonic acid
Other names
(p-Nitrophenyl)arsonic acid; 4-Nitrobenzenearsonic acid
Identifiers
ChemSpider 60190
Jmol-3D images Image
PubChem 66826
Properties
Molecular formula
C6H6AsNO5
Molar mass 247.04 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Nitarsone is an organoarsenic compound that is used in poultry production as a feed additive to increase weight gain, improve feed efficiency, and prevent blackhead disease.[1] It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.[2]

Nitarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry, along with roxarsone, arsanilic acid, and carbarsone.[3] Following the 2011 suspension of roxarsone sales in the United States, however, it is believed to be the only arsenical animal drug currently marketed in the U.S.[3][4] In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place.[5] When the withdrawals occur, nitarsone will be the only arsenical approved for use in food animals in the U.S.


References

  1. U.S. Food and Drug Administration. "Animal Drugs @ FDA".
  2. Zoetis. "Histostat: Type A Medicated Feed Article".
  3. 3.0 3.1 U.S. Food and Drug Administration (June 8, 2011). "Questions and Answers Regarding 3-Nitro (Roxarsone)".
  4. Sabrina Tavernise (May 11, 2013). "Study Finds an Increase in Arsenic Levels in Chicken". New York Times.
  5. U.S. Food and Drug Administration (September 20, 2011). "FDA Response to Citizen Petition on Arsenic-based Animal Drugs".