Nimorazole

Nimorazole
Systematic (IUPAC) name
4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
6506-37-2
P01AB06 QP51AA06
PubChem CID 23009
ChemSpider 21533
UNII 469ULX0H4G Yes
KEGG D07352 Yes
Chemical data
Formula C9H14N4O3
226.23 g/mol
 Yes (what is this?)  (verify)

Nimorazole (INN) is a nitroimidazole anti-infective.[1] It is also being investigated for the treatment of head and neck cancer.[2][3]

References

  1. ↑ Roy, R. B.; Laird, S. M.; Heasman, L. (1975). "Treatment of trichomoniasis in the female. A comparison of metronidazole and nimorazole". The British Journal of Venereal Diseases 51 (4): 281–284. PMC 1046566. PMID 1098732.
  2. ↑ Henk, J. M.; Bishop, K.; Shepherd, S. F. (2003). "Treatment of head and neck cancer with CHART and nimorazole: Phase II study". Radiotherapy and Oncology 66 (1): 65–70. doi:10.1016/S0167-8140(02)00284-0. PMID 12559522.
  3. ↑ Clinical trial number NCT01507467 for "IAEA-HypoX. Accelerated Radiotherapy With or Without Nimorazole in Squamous Cell Carcinoma of the Head and Neck" at ClinicalTrials.gov