Nifuroxazide
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| Systematic (IUPAC) name | |
|---|---|
| 4-Hydroxy-N'-[(5-nitrofuran-2-yl)methylene]benzohydrazide | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Oral | |
| Identifiers | |
965-52-6  | |
| A07AX03 | |
| PubChem | CID 5337997 |
| ChemSpider |
4495115  |
| UNII |
PM5LI0P38J |
| KEGG |
D07111 |
| ChEMBL |
CHEMBL244888 |
| Chemical data | |
| Formula | C12H9N3O5 |
| 275.2 g/mol | |
|
SMILES
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| (what is this?) (verify) | |
Nifuroxazide (INN) is an oral nitrofuran antibiotic, patented since 1966[1] and used to treat colitis and diarrhea in humans and non-humans.[2] It is sold under the brand names Ambatrol, Antinal, Bacifurane, Diafuryl (France), Diax (Egypt), Nifrozid, Ercefuryl (Romania, Czech Republic), Erfuzide (Thailand), Endiex (Slovakia), Nifuroksazyd (Poland), Pérabacticel (France), Pentofuryl (Germany), Topron, Enterovid (Latin America), Eskapar (Mexico), Antinal (Egypt), Apazid (Morocco) and Septidiaryl. It is sold in capsule form and also as a suspension.
History
Maurice Claude Ernest Carron patented the drug in the United States in 1966.[1] Subsequent patents issued to Germano Cagliero of Marxer S.p.A describe the use of nifuroxazide as an antibiotic used to treat livestock.[2]
Notes
- ↑ 1.0 1.1 USPTO No. 3290213 |http://www.google.com/patents?id=f2dwAAAAEBAJ
- ↑ 2.0 2.1 USPTO No 4093746 |http://www.google.com/patents?vid=USPAT4093746
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