Naringenin 7-O-methyltransferase

Naringenin 7-O-methyltransferase
Identifiers
EC number 2.1.1.232
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Naringenin 7-O-methyltransferase (EC 2.1.1.232, NOMT) (full systematic name S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase) is a methyltransferase isolated from rice, which catalyzes the biosynthesis of sakuranetin.[1]

This enzyme catalyses the following chemical reaction:

S-adenosyl-L-methionine + (2S)-naringenin \rightleftharpoons S-adenosyl-L-homocysteine + (2S)-sakuranetin

While the enzyme is not present in healthy rice leaves, it can be induced by treatment with ultraviolet radiation, jasmonic acid and copper chloride.[1]

References

  1. 1.0 1.1 Rakwal, R.; Agrawal, G.K.; Yonekura, M; Kodama, O. (2000). "Naringenin 7-O-methyltransferase involved in the biosynthesis of the flavanone phytoalexin sakuranetin from rice (Oryza sativa L.)". Plant Science 155: 213–221. doi:10.1016/s0168-9452(00)00223-5. PMID 10814825.

External links