Nafenopin

Nafenopin
Names

IUPAC name 2-Methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
Identifiers
CAS Registry Number	3771-19-5^N
ChEBI	CHEBI:7449^N
ChEMBL	ChEMBL1909070^N
ChemSpider	18456^Y
InChI InChI=1S/C20H22O3/c1-20(2,19(21)22)23-16-12-10-15(11-13-16)18-9-5-7-14-6-3-4-8-17(14)18/h3-4,6,8,10-13,18H,5,7,9H2,1-2H3,(H,21,22)^Y Key: XJGBDJOMWKAZJS-UHFFFAOYSA-N^Y InChI=1S/C20H22O3/c1-20(2,19(21)22)23-16-12-10-15(11-13-16)18-9-5-7-14-6-3-4-8-17(14)18/h3-4,6,8,10-13,18H,5,7,9H2,1-2H3,(H,21,22) InChI=1S/C20H22O3/c1-20(2,19(21)22)23-16-12-10-15(11-13-16)18-9-5-7-14-6-3-4-8-17(14)18/h3-4,6,8,10-13,18H,5,7,9H2,1-2H3,(H,21,22) Key: XJGBDJOMWKAZJS-UHFFFAOYSA-N
Jmol-3D images	Image
KEGG	C11371^N
PubChem	19592
SMILES O=C(O)C(Oc1ccc(cc1)C3c2ccccc2CCC3)(C)C
Properties
Molecular formula	C₂₀H₂₂O₃
Molar mass	310.39 g·mol⁻¹
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
N verify (what is: Y/N?)
Infobox references

Nafenopin is a hypolipidemic agent.

References

Lipid modifying agents (C10)

GI tract

Cholesterol absorption inhibitors, NPC1L1	Ezetimibe SCH-48461

Bile acid sequestrants/resins (LDL)	Cholestyramine Colestipol Colestilan Colextran Colesevelam

Statins (HMG-CoA reductase, LDL)	Simvastatin^# Atorvastatin Fluvastatin Lovastatin Mevastatin Pitavastatin Pravastatin Rosuvastatin Cerivastatin^‡

Niacin and derivatives (HDL and LDL)	Niceritrol Niacin Nicofuranose Aluminium nicotinate Nicotinyl alcohol Acipimox

MTTP inhibitors (VLDL)	Dirlotapide Lomitapide Mitratapide

Fibrates (PPAR)	Clofibrate^‡ Bezafibrate Aluminium clofibrate Gemfibrozil Fenofibrate Simfibrate Ronifibrate Ciprofibrate Etofibrate Clofibride Clinofibrate

CETP inhibitors (HDL)	Anacetrapib^† Dalcetrapib^§ Evacetrapib^† Torcetrapib^§

Combinations

Other

Dextrothyroxine^‡
Probucol
Tiadenol
Benfluorex
Meglutol
Omega-3-triglycerides
Magnesium pyridoxal 5-phosphate glutamate
Policosanol
Lapaquistat^§
Mipomersen
Alipogene tiparvovec

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of nutrition

Description	Vitamins metabolism Cofactors Metal metabolism Fats metabolism intermediates lipoproteins Sugars Glycolysis enzymes Glycogenesis and glycogenolysis intermediates Fructose and galactose intermediates

Disease	Vitamins Carbohydrate Lipid storage Metals Other Symptoms and signs eponymous

Treatment	Drugs obesity lipid-modifying Vitamins Mineral supplements