NOL8

Nucleolar protein 8

Identifiers

NOL8 ; C9orf34; NOP132; bA62C3.3; bA62C3.4

External IDs

OMIM: 611534 MGI: 1918180 HomoloGene: 41210 GeneCards: NOL8 Gene

Gene ontology
Molecular function	• nucleotide binding • protein binding • poly(A) RNA binding
Cellular component	• nucleus • nucleolus • cytoplasm
Biological process	• DNA replication • rRNA processing • positive regulation of cell growth
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000198000

ENSMUSG00000021392

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 9:
92.3 – 92.33 Mb

Chr 13:
49.65 – 49.68 Mb

PubMed search

Nucleolar protein 8 is a protein that in humans is encoded by the NOL8 gene.^[1]^[2]

Interactions

NOL8 has been shown to interact with RRAGA^[3] and NIP7.^[3]

References

↑ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. CS1 maint: Date and year (link)
↑ "Entrez Gene: NOL8 nucleolar protein 8".
↑ 3.0 3.1 Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (Feb 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J. Biol. Chem. 279 (9): 8343–50. doi:10.1074/jbc.M305935200. PMID 14660641. CS1 maint: Date and year (link)

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T (2001). "Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B". J. Biol. Chem. 276 (10): 7246–57. doi:10.1074/jbc.M004389200. PMID 11073942.
Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J. Biol. Chem. 279 (9): 8343–50. doi:10.1074/jbc.M305935200. PMID 14660641.
Jinawath N, Furukawa Y, Nakamura Y (2004). "Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer". Cancer Sci. 95 (5): 430–5. doi:10.1111/j.1349-7006.2004.tb03227.x. PMID 15132771.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.