NCAPG

Non-SMC condensin I complex, subunit G
Identifiers
SymbolsNCAPG ; CAPG; CHCG; NY-MEL-3; YCG1
External IDsOMIM: 606280 HomoloGene: 44071 GeneCards: NCAPG Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez6415154392
EnsemblENSG00000109805ENSMUSG00000015880
UniProtQ9BPX3n/a
RefSeq (mRNA)NM_022346NM_019438
RefSeq (protein)NP_071741NP_062311
Location (UCSC)Chr 4:
17.81 – 17.85 Mb
Chr 5:
45.67 – 45.7 Mb
PubMed search

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene.[1][2][3] CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

Interactions

NCAPG has been shown to interact with DNMT3B.[4]

References

  1. Jäger D, Stockert E, Jäger E, Güre AO, Scanlan MJ, Knuth A et al. (Aug 2000). "Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library". Cancer Res. 60 (13): 3584–91. PMID 10910072. Vancouver style error (help)
  2. Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts". J. Biol. Chem. 276 (8): 5417–20. doi:10.1074/jbc.C000873200. PMID 11136719.
  3. "Entrez Gene: NCAPG non-SMC condensin I complex, subunit G".
  4. Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT et al. (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359.

Further reading