N-Oxalylglycine
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Names | |
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IUPAC name
N-Oxalylglycine | |
Other names
[(Carboxymethyl)amino](oxo)acetic acid | |
Identifiers | |
Abbreviations | NOG |
5262-39-5 ![]() | |
ChEBI | CHEBI:44482 ![]() |
ChEMBL | ChEMBL90852 ![]() |
ChemSpider | 2338366 ![]() |
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Jmol-3D images | Image Image |
MeSH | oxalylglycine |
PubChem | 3080614 |
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Properties | |
Molecular formula |
C4H5NO5 |
Molar mass | 147.09 g·mol−1 |
Appearance | colourless crystals |
log P | 1.232 |
Acidity (pKa) | 2.827 |
Basicity (pKb) | 11.170 |
Related compounds | |
Related alkanoic acids |
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Related compounds |
N-Acetylglycinamide |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
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Infobox references | |
N-Oxalylglycine is the organic compound with the formula HO2CC(O)NHCH2CO2H. This colourless solid is used as an inhibitor of α-ketoglutarate-dependent enzymes.[1] It is isosteric with α-ketoglutaric acid. Such enzymes are pervasive and, for example, are required for the synthesis of 4-hydroxyproline.
References
- ↑ Hausinger, R. P."Fe(II)/α-ketoglutarate-dependent hydroxylases and related enzymes" Critical Reviews of Biochemical Molecular Biology 2004, 39: pp 21-68. doi:10.1080/10409230490440541